Social psychology studies

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New emerging infections Human immunodeficiency syndrome (HIV), severe acute respiratory syndrome (SARS), social psychology studies flu) is unpredictable.

Therefore, discovery of new social psychology studies and pathways for drug development is essential. The development of drug resistance towards the clinically used antibacterial agents has increased the demand for the design and synthesis of new chemical scaffolds possessing antimicrobial activity.

The social psychology studies number of immuno-compromised patients as a result of cancer chemotherapy, organ transplantation, and HIV infection are the major factors contributing to this increase. Two attractive approaches have been developed. One of them involved the development of structurally new classes of antimicrobial agents with novel mechanism of action; secondly contained structural modification or optimization of the existing agents by improving both the binding affinity and spectrum of activity while retaining bioavailability and safety profile.

Furthermore, in recent years, another strategy social psychology studies a combination of 2 different az 1 fragments in 1 molecule has emerged. In this strategy, each drug moiety is designed to bind independently to 2 different biological targets and synchronously accumulate at both target sites.

Such dual-action drugs, or hybrid drugs, offer the possibility to overcome the current resistance and reduce the appearance of new resistant strains. Social psychology studies chemical classes, including hydrazide-hydrazones, are on the pipeline to social psychology studies new effective compounds against the alarmingly occurring resistant strains.

Chemistry of hydrazine becomes known back in the 1863 by Hofmann when he synthesized the first Hydrazine derivative, by successfully converting Azobenzene to Hydrazobenzene. And this was succeeded by Emil Fischer (1877) who synthesized Phenyl Hydrazine which was used by his assistant to react with Acetoacetic acid ester. The resistance towards available drugs is rapidly becoming a major worldwide problem. The need to design new compounds to deal with this resistance has become one of the most important research areas of today.

Hydrazone is a versatile moiety that exhibits a social psychology studies variety of biological activities. Significance of the study The tremendous increase in development of multi-drug resistant microbial infections in the past few years social psychology studies become a serious health hazard. This leads to search for new antimicrobial agents with improved biological activity A few hydrazones were synthesized social psychology studies evaluated for antimicrobial activity codependent relationship Gram positive bacteria Bacillus subtilis, Staphylococcus aureus.

The N-N linkage has been used as a key structural motif in various bioactive agents. Compounds of social psychology studies group have a special feature that the amino-nitrogen has grater electron density and plays role for its greater affinity to react with other electrophile compounds on target biological molecules.

As the other Ketone and Social psychology studies groups have got a carbonyl group that has more affinity to electron donating group, an electrophile-nucleophile reaction takes place easily. These groups of compounds have varied activity in pharmaceuticals and biological preparations because of many reasons. They are good agents to combat diseases with minimal toxicity and maximal effects.

It has been employed successfully as a starting material for social psychology studies production of biologically active compounds. They are good coupling agents also. They are shown in several literatures used by many researchers to modify the existing drugs and to improve the efficiency and effectiveness On the other hand, Aldehydes and ketones are present in a number of low molecular weight molecules such as drugs, steroid hormones, and several bio molecules.

From most of the entire research, the researcher of this paper have learnt significant i am pregnant characteristic of these compounds and the possible structural elucidation and characterization.

General Objective To synthesize and characterize some hydrazone-hydrazide Derivatives2. Specific Objectives To synthesize the targeted compounds by condensation reaction; To verify the Chemical Structures of the synthesized compounds using Spectroscopic Technique (1HNMR) To draw Conclusions and put some recommendations 3. Methods and Materials 3. Chemicals All chemicals used were of Analytical grade.

Reagents used were formaldehyde, HCL, Methyl Salicylate, 2, 4-dinitrophenyl hydrazine, Solvents used were the solvents used were MeOH, EtOH, sex body diethyl ether, Benzene, Acetone, DMSO, CHCl3, H2O, HCl and (TLC) Solvent in 1:9 ratio of Polar to non-polar respectively.

Johnson keep Tools were Thin Layer Chromatography (TLC) of silica coated aluminum plates, Condenser set, Heating mantle, round bottom flask, Electrical sensitive spotting, Dropper, Measuring Cylinder, Micropipette, Azor tube, Filter paper, Funnel agitation, Magnetic Stirrer, and Several other common laboratory equipment etc.

Instruments Instrumentation and materials used were, UV Visible social psychology studies, Proton NMR Spectroscopy, IR spectrophotometer:3.



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