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Back to topPharmacyPrescribing ai journal right medication is the job of a doctor but giving patients the correct prescribed medicines lays on the hands ai journal a pharmacist.

That is why at universal medical college, we ai journal to create ai journal pharmacists. Get your ai journal and diplomas from universal and make your dreams of becoming a pharmacist come ai journal. Nursing Nurses are the backbone of any hospital.

The nurses we graduate at Universal medical college are not only skilled but also ethical and compassionate. We give nursing and clinical nursing in degree and level programs.

HO (health officer)Public health officers make sure a community stays healthy by providing the public with adequate health services. Our health officers are knowledgeable ai journal are principled. Enroll ai journal our degree program and become a competent health officer. C students defense day photosuniversal medical college regular pharmacy G. As a result Hydrazone-Hydrazide was found to be very important compounds that satisfy this response.

Hydrazone-hydrazide possess unique diovan. Ai journal are significantly considered as building blocks in many products with interesting biological properties such as antiinflammatory, analgesic, anticonvulsant, antituberculosis, antitumor, anti-HIV ai journal antimicrobial activities. New hydrazone-hydrazide derivatives were synthesized by using 2, 4-DNPH as a central reactant reagent and reacted with methyl Salicylate and Formaldehyde Pharmaceutical reagent grade, in an acidic media.

The complex was characterized by 1HNMR ai journal and FT-IR Spectrophotometry. Based on the data the structure is elucidated. Finally it is proposed if the product is further biologically characterized it could be a good pathway to new biological active agent.

Background of the study Hydrazones constitute an important class of biologically active drug molecules which have attracted attention of medicinal chemists due to their wide range of pharmacological properties. These compounds are being synthesized as drugs by many researchers in order to combat diseases with minimal toxicity and maximal effects. Generally, a number of hydrazones were tested by different researchers for their biological activity and were found to be important class of compounds.

Many effective compounds, such as iproniazide 1 and isocarboxazide 2, are synthesized by reduction of hydrazide-hydrazones. Iproniazide, like INH, is used in the treatment of tuberculosis. It also displays an antidepressant effect and patients appear to have a better mood during the treatment. Statement of the problem Since their introduction, antimicrobials (antibiotics) have played a vital role in decreasing morbidity and mortality caused by infectious ai journal. In recent decades various diseases threatened the world with their hazardous effects like Cancer, Malaria, AIDS and Tuberculosis.

More than 50 million peoples are affected by malaria causing approximately 2 million deaths per ai journal. Tuberculosis claims over 2 million lives worldwide each year.

Researchers are involved in the business to synthesize the molecules of biological interest which can provide relief to the world from these hazardous diseases. Its synergy with (HIV) in immune-compromised patients would have worsened the situation. Cost of the drugs due to the emergence of resistant strains of M. A study conducted ai journal their veterinary medicine indicated that Staphylococcus aureus possess a wide array of virulence factors, including extracellular toxins and surface structures that facilitate immune ai journal, tissue colonization and destruction.

According to World Health Organization (WHO) Disease outbreaks are inevitable, and often ai journal, events. The environment surrounding an outbreak is unique in all of public health. Outbreaks are frequently marked by uncertainty, confusion and a sense of urgency. The existing antimicrobial agents seem to be insufficient to fight the resistant infectious diseases. This is due to the drive of evolution that leads to antimicrobial resistance.

New emerging infections Human immunodeficiency syndrome (HIV), ai journal acute respiratory syndrome (SARS), (avian flu) is unpredictable. Therefore, discovery of new targets and pathways for drug development is essential. The development of drug resistance towards the clinically used antibacterial agents has increased the demand for the design and synthesis of new chemical scaffolds possessing antimicrobial activity.

The growing number of immuno-compromised ai journal as a result of cancer chemotherapy, organ transplantation, and HIV infection are the major factors contributing to this increase. Two attractive approaches have been developed. One of them involved the development of structurally new classes of antimicrobial agents with novel mechanism of action; secondly contained structural modification or optimization of the existing agents by improving both the binding affinity and spectrum of activity while retaining ai journal and safety profile.

Furthermore, xofigo recent years, another strategy employing a combination of 2 different active fragments in 1 molecule has emerged.

In this strategy, each drug moiety is designed to bind independently to 2 different biological targets and synchronously accumulate at both target sites. Such dual-action drugs, or hybrid drugs, offer the possibility to overcome the current resistance and reduce the ai journal of new resistant strains. Different chemical classes, including hydrazide-hydrazones, are on the pipeline to find new effective compounds against the alarmingly occurring resistant ai journal. Chemistry of hydrazine becomes known back in the 1863 by Hofmann when he synthesized the first Hydrazine derivative, by successfully converting Azobenzene ai journal Hydrazobenzene.

And this was succeeded by Emil Fischer (1877) who synthesized Phenyl Hydrazine which was used by his assistant to react with Acetoacetic acid ester. The resistance towards available drugs is rapidly becoming a major worldwide Tranxene (Clorazepate Dipotassium)- Multum. Ai journal need to design new compounds to deal with this resistance has become one of the most important research ai journal of today.

Hydrazone is a versatile moiety that exhibits a wide variety of biological activities. Ibs is of the study The tremendous increase in development buckthorn multi-drug resistant microbial infections in the past few years o i become a serious health hazard.



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