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Plasma Cytochrome c release after envenomations by BaV and CdV. Tonello for helpful comments and suggestions. Author ContributionsConceived and designed the experiments: IZ PC CM. Kasturiratne A, Wickremasinghe AR, de Silva N, Gunawardena NK, Pathmeswaran A, et al. PLoS Med 5: e218. Chippaux JP (1998) Snake-bites: appraisal of the global situation. World Health Organisation (2007) Rabies and envenomings: a neglected public health issue. PLoS Med 3: e150. Warrell D (2004) Epidemiology, clinical features and management of snake bites in Central and South America.

In: Cognitive dissonance and building customer feedback JA, Lamar WW, editors. The Venomus Reptiles of the Western Hemisphere, vol I. Ithaca: Cornell University Press. Fan H, Cardoso J (1995) Clinical toxicology of snake bites in South America. In: Mayer J, White J, editors. Handbook of Clinical Toxicology of Animal Venoms and Poisons. Azevedo-Marques M, Hering S, Cupo P (2003) Acidente crotalico.

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In: Kini RM, editor. Azevedo-Marques MM, Cupo P, Coimbra TM, Hering SE, Rossi MA, et al. Barraviera B, Lomonte B, Tarkoski A, Hanson L, Meira DA (1995) Acute-phase reactions, including cytokines, in patients bitten by Bothrops and Crotalus snake in Brazil. Journal of Venomous Animala and Toxins.

Piccinini AM, Midwood KS (2010) DAMPening inflammation by modulating TLR signalling. Sci Signal 2: pe6. Di Virgilio F (2007) Liaisons dangereuses: P2X(7) and the inflammasome. Burnstock G (2007) Purine and pyrimidine receptors. Sport helps people to fight stress M, Caccin P, Chiavegato A, Pizzo P, Carmignoto G, et al. Martinon F (2008) Detection of immune danger sport helps people to fight stress by NALP3.

Kerkweg U, sport helps people to fight stress Groot Sport helps people to fight stress (2005) ATP-induced calcium increase as a potential first signal in mechanical tissue trauma. A laser scanning microscopic study on cultured mouse skeletal myocytes. Zhang Q, Raoof M, Chen Y, Sumi Y, Sursal T, et al. Kono H, Rock KL (2008) How dying cells alert the immune system to danger.

Bianchi ME (2007) DAMPs, PAMPs and alarmins: all we need to know about danger.

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