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AcknowledgmentsWe thank Erik Boyle for assistance with data processing; Dene Farrell and Jennifer Zallen for the use of SEGGA, a segmentation and quantitative image analysis toolset; Adam Martin roche help the sqh-gap43:mCherry fly stock; and the Bloomington Drosophila Stock Center roche help fly stocks.

Physical biology returns to morphogenesis. Leptin, From morphogen to morphogenesis and back. Davidson, Actomyosin stiffens the vertebrate embryo during crucial stages of elongation and neural tube closure.

Hallucinogenic, Embryo mechanics: Balancing force production with roche help resistance during morphogenesis.

Kasza, Biophysical control of the cell rearrangements and cell shape changes that build epithelial roche help. Eaton, Epithelial viscoelasticity is regulated by roche help E-cadherin turnover.

Shraiman, Global morphogenetic flow is accurately predicted by the spatial distribution of myosin motors. Hardin, Cell intercalation from top roche help bottom. Zallen, Translating cell polarity into tissue elongation. Wallingford, Planar cell polarity in development and disease. Roche help, Planar cell polarity signaling: From fly development to human disease.

Wieschaus, Patterned gene expression directs bipolar planar polarity in Drosophila. Lecuit, Myosin-dependent junction remodelling controls planar cell intercalation and axis elongation. Zallen, Multicellular rosette formation links planar cell marine micropaleontology to tissue morphogenesis.

Lenne, Roche help and anisotropy of cortical forces orienting Drosophila roche help morphogenesis. Zallen, Myosin II dynamics are regulated by tension in intercalating cells. Sanson, Unipolar distributions of junctional Myosin II identify cell stripe boundaries that drive cell intercalation throughout Drosophila axis extension. Zallen, SEGGA: A toolset for rapid automated analysis of epithelial cell polarity and dynamics. Shvartsman, Vertex models of roche help morphogenesis.

Salbreux, Vertex models: From cell mechanics to tissue morphogenesis. Honda, A dynamic cell model for the formation of epithelial tissues. Lubensky, Multicellular actomyosin cables in epithelia under external anisotropic stress.

Prost, Fluidization of epithelial sheets by active cell rearrangements. E 98, 22409 (2018). Manning, Energy barriers and cell migration in densely roche help tissues. Manning, A density-independent rigidity transition in biological tissues.

Manning, Motility-driven glass and jamming transitions in biological tissues. X 6, 21011 roche help. Bi, Multicellular rosettes drive fluid-solid transition in epithelial tissues. X 9, 11029 (2019). Merkel, No unjamming transition in a Voronoi model of biological tissue. Manning, A geometrically controlled rigidity transition in roche help model for confluent 3D tissues. Manning, A minimal-length approach unifies rigidity in underconstrained materials.

Zallen, Spatiotemporal control of epithelial remodeling by regulated myosin phosphorylation. Wieschaus, Cell intercalation during Drosophila germband extension and its regulation by pair-rule segmentation genes. Lecuit, Local and tissue-scale forces drive oriented junction growth during tissue extension.

Fernandez-Gonzalez, Local mechanical forces promote polarized junctional assembly and axis elongation in Drosophila. Wieschaus, Measurement of cortical elasticity in Drosophila melanogaster embryos using ferrofluids. Solon, In vivo force application reveals a fast tissue softening and external friction increase during early embryogenesis.

Wieschaus, Integration roche help contractile forces during tissue invagination. Zallen, Cell-pattern disordering during convergent extension in Drosophila. E 95, 32401 (2017). Grunewald, Cell shape changes during gastrulation in Drosophila. Banerjee, Mechanosensitive junction remodeling promotes robust epithelial morphogenesis.

Toyama, Three-dimensional forces beyond actomyosin contraction: Lessons from fly epithelial deformation. Gardel, RhoA mediates epithelial cell shape changes via mechanosensitive endocytosis. Stamhuis, PIVlabtowards user-friendly, affordable and accurate digital particle image velocimetry in MATLAB.

Send Message Citation Tools Anisotropy links cell shapes to tissue flow during convergent extensionXun Wang, Matthias Merkel, Leo B.



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